I argue that self-actualization is achievable with the use of mind-manifesting substances known as psychedelics. These substances include singular drugs such as LSD, psilocybin (magic mushrooms), mescaline (peyote), and to a lesser extent MDMA (ecstasy) and THC (cannabis). I will refer to use of psychedelics for the purpose of self-actualization as ‘psychedelic travel.’ Psychedelic travel may be as efficient and ethical a means of self-actualization as geographical travel. For example, for fewer costs, it may bring about similar positive environmental, cultural, and personal benefits, including greater empathy, creativity, and authenticity.