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<br> <br><br><br> <br><br>Acute effects<br><br> <br><br><br><br> <br><br>The effect of cocaine administration will vary depending on how it is used. Cocaine can cause hyperstimulation, alertness and euphoria when smoked or injected. It also causes feelings of competence, strength, and increased energy. Similar highs and excitement can be experienced by injecting amphetamines. The effects are less severe and more damaging for addicts who inhale cocaine through their nose.<br><br> <br><br><br><br> <br><br>Addicts who smoke the drug may develop pneumothorax or pneumomediastinum, causing chest pain, shortness of breath, or both. Cocaine use can cause chest problems ("cocaine heart pain") as well as myocardial and cardiac ischemia. However, this mechanism remains elusive. There have been reports of arrhythmias, conduction abnormalities and other symptoms. Sudden death can result from cardiac effects. "Marathon", a continuous use that lasts f